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Macrophage-mediated inflammation in skin wound healing

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During oxidative stress, the oxidized DJ-1 may translocate to the outer membrane of mitochondria and it has been shown to prevent MPP + induced cell death, the mechanism of which remains unclear [12]

At a site of inflammation, oxidative stress is mediated by reactive oxygen species (ROS) generated primarily by activated leukocytes (neutrophils, macrophages, eosinophils)